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Phenyl butyrate

  • Name Phenyl butyrate
  • CAS 4346-18-3
  • Purity 99%
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Product Details

Factory Supply industrial standard Phenyl butyrate 4346-18-3 In Stock

  • Molecular Formula: C10H12O2
  • Molecular Weight: 164.204
  • Vapor Pressure: 0.0648mmHg at 25°C 
  • Refractive Index: 1.497 
  • Boiling Point: 230.7 °C at 760 mmHg 
  • Flash Point: 90.3 °C 
  • PSA: 26.30000 
  • Density: 1.025 g/cm3 
  • LogP: 2.39210 

Phenyl butyrate(Cas 4346-18-3) Usage

General Description

Phenyl butyrate is a chemical compound that is composed of a phenyl group and a butyric acid group. It is a derivative of butyric acid and is commonly used as a treatment for urea cycle disorders, which are genetic metabolic disorders that affect the body's ability to break down ammonia. Phenyl butyrate works by helping to remove excess ammonia from the body and is often taken orally as a medication to manage the symptoms of these disorders. Additionally, it has been studied for its potential anti-cancer properties and has shown promise in inhibiting the growth of cancer cells. Overall, phenyl butyrate is a versatile chemical with diverse pharmacological properties.

InChI:InChI=1/C10H12O2/c1-2-6-10(11)12-9-7-4-3-5-8-9/h3-5,7-8H,2,6H2,1H3

4346-18-3 Relevant articles

Mechanically induced solvent-free esterification method at room temperature

Zheng, Lei,Sun, Chen,Xu, Wenhao,Dushkin, Alexandr V.,Polyakov, Nikolay,Su, Weike,Yu, Jingbo

, p. 5080 - 5085 (2021/02/05)

Herein, we describe two novel strategies...

Cobalt-Catalyzed Radical Hydroamination of Alkenes with N-Fluorobenzenesulfonimides

Lv, Guowei,Meng, Qi,Qin, Tao,Xiong, Tao,Zhang, Ge,Zhang, Qian

supporting information, p. 25949 - 25957 (2021/11/01)

An efficient and general radical hydroam...

Activity and specificity studies of the new thermostable esterase EstDZ2

Myrtollari, Kamela,Katsoulakis, Nikolaos,Zarafeta, Dimitra,Pavlidis, Ioannis V.,Skretas, Georgios,Smonou, Ioulia

, (2020/09/16)

In this paper, we study the activity and...

Electrochemical Hydrogenation with Gaseous Ammonia

Li, Jin,He, Lingfeng,Liu, Xu,Cheng, Xu,Li, Guigen

supporting information, p. 1759 - 1763 (2019/01/16)

As a carbon-free and sustainable fuel, a...

4346-18-3 Process route

methoxybenzene
100-66-3

methoxybenzene

butyric acid
107-92-6

butyric acid

phenyl butanoate
4346-18-3

phenyl butanoate

1-(4-methoxyphenyl)-1-butanone
4160-51-4

1-(4-methoxyphenyl)-1-butanone

Conditions
Conditions Yield
HZSM-5 zeolite; at 149.9 ℃; for 48h; Yield given. Yields of byproduct given;
HZSM-5 zeolite; at 119.9 ℃; for 48h; Yield given. Yields of byproduct given;
butyric acid
107-92-6

butyric acid

phenol
108-95-2,27073-41-2

phenol

phenyl butanoate
4346-18-3

phenyl butanoate

Conditions
Conditions Yield
With tetrachloromethane; triethylamine; triphenylphosphine; In acetonitrile; for 4h; Ambient temperature;
90%
butyric acid; With 7,7-dichlorocyclohepta-1,3,5-triene; triethylamine; In dichloromethane; at 20 ℃; for 0.416667h; Inert atmosphere;
phenol; In dichloromethane; at 20 ℃; Inert atmosphere;
88%
With thionyl chloride;
84%
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃; for 18h; Inert atmosphere;
83%
With acid activated Indian bentonite; In toluene; for 8h; Heating;
82%
butyric acid; With dmap; dicyclohexyl-carbodiimide; In dichloromethane; at 0 ℃; for 0.5h;
phenol; In dichloromethane; at 0 ℃; for 6h;
60%
With potassium hypophosphite; iodine; sodium sulfate; In neat (no solvent); at 20 ℃; for 0.333333h; Milling; Green chemistry;
53%
With sulfuric acid; benzene; unter Entfernen des entstehenden Wassers;
With butyryl-sulfuric acid; at 0 ℃;
With Fuller's Earth; at 180 ℃;

4346-18-3 Upstream products

  • 359-48-8
    359-48-8

    trifluoroacetyl peroxide

  • 495-40-9
    495-40-9

    propiophenone

  • 141-75-3
    141-75-3

    butyryl chloride

  • 108-95-2
    108-95-2

    phenol

4346-18-3 Downstream products

  • 1551-44-6
    1551-44-6

    cyclohexyl butyrate

  • 99421-51-9
    99421-51-9

    (1,2-dichloro-but-1-enyl)-phenyl ether

  • 2887-61-8
    2887-61-8

    2-hydroxybutyrophenone

  • 1009-11-6
    1009-11-6

    1-(4-hydroxyphenyl)-butan-1-one

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